People

Steve Goldstein, PhD

Director, Orthopaedic Research Laboratories

Henry Ruppenthal Family Professor of Orthopaedic Surgery and Bioengineering

Professor of Surgery

Professor of Mechanical Engineering and Applied Mechanics

Senior Research Scientist, Institute of Gerontology

Director, Center for Biomedical Engineering Research

Professor of Biomedical Engineering

Associate Dean for Research and Graduate Studies, Medical School

EDUCATION

1968-72 Exeter Township High School, Berks County, Pennsylvania, Diploma

1972-76 Tufts University, B.S. in Mechanical Engineering

1976-78 The University of Michigan, M.S. in Bioengineering

1978-81 The University of Michigan, Ph.D. in Bioengineering

PUBLICATIONS

Completed Publications in Scientific Journals

Peer-Reviewed Publications

1. Crochetiere WJ, Goldstein SA, Granger GV, Ireland J: The Granger Orthosis for Radial Nerve Palsy. Orthotics and Prosthetics, 29(4): 27-31, 1975.

2. Goldstein SA: Biomechanical Aspects of Cumulative Trauma to Tendons and Tendon Sheaths. PhD Thesis, The University of Michigan, May 1981.

3. Foulke J, Goldstein SA, Armstrong TJ: An EMG Preamplifier System for Biomechanical Events. Journal of Biomechanics, 14(6):437-438, 1981.

4. Armstrong TJ, Foulke JA, Joseph BS, Goldstein SA: Investigation of Cumulative Trauma in a Poultry Processing Plant. American Industrial Hygiene Journal (43)2:103-116, 1982.

5. Zand M, Goldstein SA, Matthews LS: Fatigue Failure of Cortical Bone Screws. Journal Biomechanics, 16(5):305-311, 1983.

6. Goldstein SA, Wilson D, Sonstegard DA, Matthews LS: The Mechanical Properties of Human Tibial Trabecular Bone as a Function of Metaphyseal Location. J Biomechanics, 16(12):965-969,1983.

7. Hankin FM, Campbell SE, Goldstein SA, Matthews LS: Hydrogen Peroxide as a Hemostatic Agent. Clinical Orthopaedics and Related Research 186:244-248, June 1984.

8. Matthews LS, Green CA, Goldstein SA: The Thermal Effects of Skeletal Fixation Pin Placement in Bone. Journal of Bone and Joint Surgery, 66A(7):1077-1083, September 1984.

9. Louis DS, Greene TL, Jacobson KE, Rasmussen C, Kolowich P, Goldstein SA: Evaluation of Normal Values for Stationary and Moving Two-Point Discrimination in the Hand. Journal of Hand Surgery 94(4):552-555, July 1984.

10. Matthews LS, Goldstein SA: Intramedullary Reamer System Helps Eliminate Flute Clogging. Orthopaedic Today, December 1984.

11. Matthews LS, Goldstein SA, Kaufer H: Experiences With Three Distinct Types of Total Knee Joint Replacement Arthroplasty. Clinical Orthopaedics and Related Research 192:97-107, January-February 1985.

12. Matthews LS, Goldstein SA, Kolowich PA, Kaufer H: Spherocentric Arthroplasty of the Knee: A Long Term and Final Follow-up Evaluation. Clinical Orthopaedics and Related Research 205:58-67, 1986.

13. Braunstein EM, Goldstein SA, Kuhn JL, Smith PA, Matthews LS: Computed Tomography and Plain Radiography in Experimental Fracture Healing. Skeletal Radiology 15:27-31, 1986.

14. Goldstein SA, Coale E, Weiss A-PC, Grossnickle M, Meller B, Matthews LS: Patellar Surface Strain. Journal of Orthopaedic Research, 4:372-377, 1986.

15. Kleerekoper M, Feldkamp LA, Goldstein SA: The Effect of Aging on the Skeleton - Implications for Changes in Tolerance. Biomechanics and Medical Aspects of Lower Limb Injuries, P-186:91-96, 1986.

16. Matthews LS, Goldstein SA: Biomechanical Considerations Regarding Failed Total Joint Arthroplasty: Causes and Prevention. Current Orthopaedics 1:27-33, 1986.

17. Goldstein SA, Matthews LS: The Physical Response of Bone to Artificial Joints. Proceedings of the Implant Manufacturing and Material Technology Conference, Chicago, Illinois, December, 1986, pp. 26-32.

18. Goldstein SA, Armstrong TJ, Chaffin DB, Matthews LS: Analysis of Cumulative Strains in Tendons and Tendon Sheaths. Journal of Biomechanics, 20(1):1-6, 1987.

19. Goldstein SA, Kuhn JL, Goulet R, Feldkamp LA, Ciarelli M, Kruger D, Jesion G, Matthews LS: The Relationship Between Three-Dimensional Architecture of Trabecular Bone and Its Mechanical Properties. Biomechanics Symposium, American Society of Mechanical Engineers 84:287-89, June 1987.

20. Wojtys EM, Goldstein SA, Redfern M, Trier E, Matthews LS: A Biomechanical Evaluation of the Lenox Hill Knee Brace. Clinical Orthopaedics and Related Research 220:179-184, July 1987.

21. Goldstein SA: The Mechanical Properties of Trabecular Bone: Dependence on Anatomic Location and Function. Journal of Biomechanics 20(11/12):1055-1061, 1987.

22. Armstrong TJ, Lawrence JF, Goldstein SA, Lifshitz YR, Silverstein BA : Ergonomics Considerations in Hand and Wrist Tendonitis. J Hand Surgery, 12A(5/2):830-837, 1987.

23. Matthews LS, Goldstein SA, Malvitz TA, Katz BP, Kaufer H: Proximal Tibial Osteotomy: Factors Which Influence the Duration of Satisfactory Function. Clinical Orthopaedics and Related Research 229:193-200, 1988.

24. Layton MW, Goldstein SA, Goulet RW, Feldkamp LA, Bole GG: Examination of Subchondral Bone Architecture in Experimental Osteoarthritis by Microscopic Computerized Axial Tomography. Journal of Arthritis and Rheumatism 31(11):1400-1405, 1988.

25. Kuhn JL, Goldstein SA, Ciarelli MJ, Matthews LS: Limitations of Canine Trabecular Bone as a Model for Human: A Biomechanical Study. Journal of Biomechanics 22(2):95-107, 1989.

26. Feldkamp LA, Goldstein SA, Parfitt AM, Jesion G, Kleerekoper M: The Direct Examination of Three Dimensional Bone Architecture In Vitro by Computed Tomography. Journal of Bone and Mineral Research 4(1): 3-11, 1989.

27. Kuhn JL, Goldstein SA, Choi K, London M, Feldkamp LA, Matthews LS: A Comparison of Trabecular and Cortical Tissue Moduli from Human Iliac Crests. Journal of Orthopaedic Research 7(6):876-884, 1989

28. Chaffin DB, Redfern MS, Erig M, Goldstein SA: Lumbar muscle size and locations from CT scans of 96 women age 40 to 63 years. Clinical Biomechanics 5(1):9-16, 1990

29. Bonadio J, Saunders TL, Tsai E, Goldstein SA, Morris-Wiman J, Brinkley L, Dolan DF, Altschuler RA, Hawkins Jr. JE, Bateman JF, Mascara T, Jaenisch R: A Transgenic Mouse Model of the Mild Dominant Form of Osteogenesis Imperfecta. PNAS 87:7145-7149, 1990.

30. Kuhn JL, Goldstein SA, Feldkamp LA, Goulet RW, Gesion G: Evaluation of a Microcomputed Tomography System to Study Trabecular Bone Structure. Journal of Orthopaedic Research 8(6):833-842, 1990

31. Kuhn JL, Goulet RW, Pappas M, Goldstein SA: Morphometric and Anisotropic Symmetries of the Canine Distal Femur. Journal of Orthopaedic Research 8:776-780, 1990

32. Bueche MJ, Phillips WA, Gordon J, Best R, Goldstein SA: The Effect of Interposition Material on Mechanical Behavior in Partial Physeal Resection--A Canine Model. Journal of Pediatric Orthopaedics 10:459-462, 1990

33. Dedrick DK, Goulet R, Huston L, Goldstein SA, Bole GG: Early Bone Changes in Experimental Osteoarthritis Using Microscopic Computed Tomography. Journal of Rheumatology 27(18):44-45, 1991.

34. Kruger DM, Herzenberg JE, Viviano DM, Hak DJ, Goldstein S.A: Biomechanical Comparison of Single and Double Pin Fixation for Acute Slipped Capital Femoral Epiphysis. Clinical Orthopaedics and Related Research 259:277-281, 1990.

35. Choi K, Kuhn JL, Ciarelli MJ, Goldstein SA: The Elastic Moduli of Human Subchondral, Trabecular, and Cortical Bone Tissue and the Size-Dependency of Cortical Bone Modulus. Journal of Biomechanics 23(11):1103-1113, 1990.

36. Cody DD, Goldstein SA, Flynn MJ: Correlations Between Vertebral Regional Bone Mineral Density and Whole Bone Fracture Load. Spine 16(2):146-154, 1991.

37. Macko VW, Matthews LS, Zwirkoski P, Goldstein SA: Joint Contact of the Ankle: Contribution of the Posterior Malleolus. Journal of Bone and Joint Surgery 73:347-351, 1991.

38. Ciarelli MJ, Goldstein S, Kuhn JL, Cody DL, Brown MB: The Orthogonal Mechanical Properties and Density of Human Trabecular Bone from the Major Metaphyseal Regions Utilizing Materials Testing and Computed Tomography. Journal of Orthopaedic Research 9:674-682, 1991

39. Majmudar G, Bole D, Goldstein SA, Bonadio J: Bone Cell Culture: A Three-Dimensional Polymer Bead Stabilized the Differentiated Phenotype and Facilitates Genetic Manipulation of Primary Osteoblastic Cells. Journal of Bone and Mineral Research 6:869-881, 1991.

40. Goldstein SA, Matthews LS, Kuhn JL, Hollister SJ: Trabecular Bone Remodeling: An Experimental Model. Journal of Biomechanics 24(S1):135-152, 1991 .

41. Hollister SJ, Fyhrie DP, Jepsen KJ, Goldstein SA: Application of Homogenization Theory to the Study of Trabecular Bone Mechanics. Journal of Biomechanics 24(9):825-839, 1991.

42. Goldstein SA, Matthews LS: The Response of Trabecular Bone to Implant Load. Orthopaedic Related Science (German Volume) 2:185-190, 1991.

43. Buchholz B, Armstrong TJ, Goldstein SA: Anthropometric Data for Describing the Kinematics of the Human Hand. Ergonomics 35(3):261-273, 1992.

44. Wong M, Lawton T, Goetinck PF, Kuhn JL, Goldstein SA, Bonadio J: Aggrecan Core Protein is Expressed in Membranous Bone of the Chick Embryo: Molecular and Biomechanical Studies of Normal and Nanomelia Embryos. Journal of Biologic Chemistry 267(8):5592-5598, 1992.

45. Smith MD, Cody DD, Goldstein SA, Cooperman AA, Matthews LS, Flynn MJ: Proximal Femur Bone Density and its Correlation to Fracture Load and Hip Screw Penetration Load. Clinical Orthopaedics and Related Research 283:244-251, 1992.

46. Choi K, Goldstein SA: The Fatigue Properties of Human Trabecular Bone Tissue. Journal of Biomechanics 25(2):1371-1381, 1992.

47. Matthews LS, Goldstein SA: The Prosthesis-Bone Interface in Total Knee Arthroplasty. Clinical Orthopaedics 276:50-55, 1992.

48. Carpenter JE, Fish DN, Huston LJ, Goldstein SA: Pull-Out Strength of Five Suture Anchors. Arthroscopy 8(3):399, 1992.

49. Hollister SJ, Kikuchi N, Goldstein SA: Do Bone Ingrowth Processes Produce a Globally Optimized Structure? Journal of Biomechanics 26(4):391-407, 1993.

50. Fyhrie PD, Fazzalari NL, Goulet R, Goldstein SA : Direct Calculation of the Surface-to-Volume Ratio For Human Cancellous Bone. Journal of Biomechanics 26:955-967, 1993.

51. Goldstein SA, Goulet R and McCubbrey D: Measurement and Significance of Three Dimensional Architecture to the Mechanical Integrity of Trabecular Bone. Calcified Tissue International. 53:S127-S133, 1993.

52. Bonadio J, Jepsen KJ, Mansoura MK, Jaenisch R, Kuhn JL, Goldstein SA: A Murine Skeletal Adaptation that Significantly Increases Cortical Bone Mechanical Properties. Implications for Human Skeletal Fragility. Journal of Clinical Investigation. 92:1697-1705, 1993.

53. Dedrick DK, Goldstein SA, Brandt KD, O'Connor BL, Goulet RW, Albrecht M: A Longitudinal Study of Subchondral Plate and Trabecular Bone in Cruciate-Deficient Dogs with Osteoarthritis Followed for Up to Fifty-Four Months. Arthritis and Rheumatism 36(10):1460-1467, 1993.

54. Lewis DB, Liggitt HD, Effmann EL, Motley ST, Teitelbaum SL, Jepsen KJ, Bonadio J, Goldstein SA, Carpenter J, and Perlmutter RM: Osteoporosis Induced in Mice by Overproduction of Interleukin-4. Proc. Natl. Acad. Sci. 90:11618-11622, 1993.

55. Bylski-Austrow, DI, Ciarelli, MJ, Kayner, DC, Matthews, LS, and Goldstein, SA: Displacement of the Menisci Under Joint Load: An in vitro Study in Human Knees. Journal of Biomechanics 27(4):421-431, 1994.

56. Goulet, RW, Goldstein, SA, Ciarelli, MJ, Kuhn, JL, Brown, MB and Feldkamp, LA: The Relationship Between the Structural and Orthogonal Compressive Properties of Trabecular Bone. Journal of Biomechanics 27(4): 375-389, 1994.

57. Glüer, C-C, Wu, CY, Jergas, M, Goldstein, SA, Genant, HK: Three Quantitative Ultrasound Parameters Reflect Bone Structure. Calcified Tissue International 55:46-52, 1994.

58. Rouleau JP, Blasier RB, Tsai E, Goldstein SA: Cannulated Hip Screws: A Study of Fixation Integrity, Cut-out Resistance, and High-Cycle Bending Fatigue Performance. Journal of Orthopaedic Trauma 8 (4):293-299, 1994.

59. Goulet JA, Rouleau JP, Mason DJ, Goldstein SA: Comminuted Fractures of the Posterior Wall of the Acetabulum. A Biomechanical Evaluation of Fixation Methods. J Bone Joint Surg. 76-A (10): 1457-1463, 1994.

60. Waanders NA, Lawton JN, Steen H, Goulet JA, Goldstein, SA: Clinical Estimation of Ilizarov Fixator Axial Stiffness Based on Wire and Half Pin Contributions. Bulletin for Hospital for Joint Diseases, 53(4): 9-12, 1995.

61. Constantz BR, Ison I, Fulmer MT, Poser RD, Smith ST, VanWagoner M, Ross J, Goldstein SA, Jupiter JB, Rosenthal DI: Skeletal Repair by in Situ Formation of the Mineral Phase of Bone. Science 267: 1796-1799, 1995.

62. McCubbrey DA, Cody DD, Peterson EL, Kuhn JL, Flynn MJ, Goldstein SA: Static and Fatigue Failure Properties of Thoracic and Lumbar Vertebral Bodies and their Relation to Regional Density. Journal of Biomechanics 28(8): 891-899, 1995.

63. Cody, DD, McCubbrey, DA, Divine, GW, Gross, GJ, Goldstein, SA: Predictive Value of Proximal Femoral Bone Densitometry in Determining Local Orthogonal Material Properties. Journal of Biomechanics 29(6):753-762, 1996.

64. Jepsen KJ, Goldstein SA, Kuhn JL, Schaffler MB, Bonadio JF: Type I collagen mutation compromises the post-yield behavior of Mov 13 long bone. Journal of Orthopaedic Research 14:493-499, 1996.

65. Fang J, Zhu Y-Y, Smiley E, Bonadio J, Rouleau JP, Goldstein SA, McCauley LK, Davidson BL, Roessler BJ: Stimulation of new bone formation by direct transfer of osteogenic plasmid genes. Proc. Natl. Acad. Sci. USA 93:5753-5758, 1996.

66. Ducy P, Desbois C, Boyce B, Pinero G, Story B, Dunstan C, Smith E, Bonadio J, Goldstein S, Gundberg C, Bradley A, Karsenty G: Osteocalcin is an Inhibitor of Bone Formation In Vivo. Nature 382:448-452, 1996.

67. Tseng KF, Bonadio JF, Stewart TA, Baker AR, Goldstein SA: Local Expression of Human Growth Hormone in Bone Results in Impaired Mechanical Integrity in the Skeletal Tissue of Transgenic Mice. Journal of Orthopaedic Research 14-4:598-604, 1996.

68. Hollister SJ, Guldberg RE, Kuelske CL, Caldwell N, Richards MR, Goldstein SA: Relative Effects of Wound Healing and Mechanical Stimulus on Early Bone Response to Porous-Coated Implants. Journal of Orthopaedic Research 14:654-662, 1996.

69. Moalli MR, Dysko RC, Rush HG, Chrisp CE, Decoster JL, Sweet KA, Goldstein SA: Oxtetracycline-induced Nephrotoxicity in Dogs Following Intravenous Administration for Experimental Bone Labeling. Laboratory Animal Science 46-5: 497-502, 1996.

70. Guldberg RE, Richards M, Caldwell NJ, Kuelske, CL, Goldstein SA: Trabecular Bone Adaptation to Variations in Porous-Coated Implant Topology. Journal of Biomechanics 30-2:147-153, 1997.

71. Germiller J, Goldstein SA: Structure and Function of Embryonic Growth Plate in the Absence of Functioning Skeletal Muscle. Journal of Orthopaedic Research, 15:362-370, 1997.

72. Moore DC, Maitra, RS, Farjo LA, Graziano GP, Goldstein SA: Restoration of Pedicle Screw Fixation With An In Situ Setting Calcium Phosphate Cement. SPINE, 22(15): 1696-1705, 1997.

73. Guldberg R, Caldwell N, Guo E, Goulet RW, Hollister SJ, Goldstein SA: Mechanical Stimulation of Tissue Repair in the Hydraulic Bone Chamber. Journal of Bone and Mineral Research, 12(8): 1295-1302, 1997.

74. Moore, DC, Frankenburg, EP, Goulet, JA, Goldstein, SA: Hip Screw Augmentation with an In Situ-Setting Calcium Phosphate Cement: An In Vitro Biomechanical Analysis. Journal of Orthopaedic Trauma, 11(8): 577-583, 1997.

75. Guo X-E, Goldstein SA: Is Trabecular Bone Tissue Different From Cortical Bone Tissue? Forma, 12(3,4): 185-196, 1997.

76. Jepsen KJ, Schaffler MB, Kuhn JL, Goulet RW, Bonadio J, Goldstein SA: Type I Collagen Mutation Alters the Strength and Fatigue Behavior of Mov13 Cortical Tissue. Journal of Biomechanics, 30(11/12): 1141-1147, 1997.

77. Carpenter JE, Kasman RA, Patel N, Lee ML, Goldstein SA: Biomechanical Evaluation of Current Patella Fracture Fixation Techniques. J Orthop. Trauma 11(5)351-356, 1997.

78. Guo X-E, Liang LC, Goldstein SA: Micromechanics of Osteonal Cortical Bone Fracture. Journal of Biomechanical Engineering, 120:112-117, February 1998.

79. Tseng, K-F, Goldstein, SA: Systemic Over-Secretion of Growth Hormone in Transgenic Mice Results in a Specific Pattern of Skeletal Modeling and Adaptation. Journal of Bone and Mineral Research, 13(4):706-715, 1998.

80. Goodman SB, Bauer TW, Carter D, Gasteleyn DP, Goldstein SA, Kyle RF, Larsson S, Stankewich CJ, Swiontkowski MF, Tencer AF, Yetkinler DN, Poser RD: Norian SRS Augmentation in Hip Fracture Treatment: Laboratory and Initial Clinical Results. CORR, 348:42-50, 1998.

81. Waanders, NA, Richards, M, Steen, H, Kuhn, JL, Goldstein, SA, Goulet, JA: Evaluation of the Mechanical Environment During Distraction Osteogenesis. CORR, 349:225-234, 1998.

82. Pezzuti JA, Morris MD, Bonadio JF, Goldstein SA: Hyperspectral Raman Imaging of Bone Growth and Regrowth Chemistry. SPIE 3261:270-276, 1998.

83. Frankenburg, EP, Goldstein, SA, Bauer, TW, Harris, SA, Poser, RD: Biomechanical and Histologic Evaluation of a Calcium Phosphate Cement. Journal of Bone and Joint Surgery, 80-A (8):1112-1124, 1998.

84. Xu T, Fisher LW, Bianco P, Longenecker G, Boskey A, Smith E, Goldstein SA, Bonadio J, Zhao C, Dominguez P, Heegaard A-M, Satomura K, Robey PG, Kulkarni AB, Sommer B, Young M: Targeted Disruption of the Biglycan Gene Leads to an Osteoporosis-Like Phenotype in Mice. Nature Genetics, 20:78-82, 1998.

85. Ladd AJC, Kinney JH, Haupt DL, Goldstein SA: Finite-Element Modeling of Trabecular Bone: Comparison with Mechanical Testing and Determination of Tissue Modulus. Journal of Orthopaedic Research, 16:622-628, 1998.

86. Labhasetwar V, Bonadio J, Goldstein S, Chen W , Levy R: A DNA Controlled-Release Coating for Gene Transfer: Transfection in Skeletal and Cardiac Muscle. Journal of Pharmaceutical Sciences, 87(11):1347-1350, 1998.

87. Goldstein SA, Bonadio J: Potential Role for Direct Gene Transfer in the Enhancement of Fracture Healing. Clinical Orthopaedics and Related Research, 355S:S154-S162, 1998.

88. Richards M, Goulet JA, Weiss JA, Waanders NA, Schaffler MB, Goldstein SA: Bone Regeneration and Fracture Healing: Experience with Distraction Osteogenesis Model. Clinical Orthopaedics and Related Research, 355S:S191-S204, 1998.

89. Zysset PK, Ominsky MS, Goldstein SA: A Novel 3D Microstructural Model for Trabecular Bone: I. The Relationship Between Fabric and Elasticity. Computer Methods in Biomechanics and Biomedical Engineering, 1:321-331, 1998.

90. Buchman SR, Sherick DG, Goulet RW, Goldstein SA: Use of Microcomputed Tomography Scanning as a New Technique for the Evaluation of Membranous Bone. Journal of Craniofacila Surgery, 9:48-54, Jan 1998.

91. Bonadio, J, Goldstein SA, Levy RJ: Gene Therapy for Tissue Repair and Regeneration. J. Advanced Drug Delivery Reviews, 33:53-69, 1998.

92. Zysset PK, Guo XE, Hoffler CE, Moore K, Goldstein SA: Mechanical Properties of Human Trabecular Bone Lamellae Quantified by Nanoindentation. Technology and Health Care, 6:429-432, 1998.

93. Timlin JA, Carden A, Morris MD, Bonadio JF, Hoffler, II CE, Kozloff KM, Goldstein SA: Spatial Distribution of Phosphate Species in Mature and Newly Generated Mammalian Bone by Hyperspectral Raman Imaging. J Biomed Optics, 4(1):28-34, 1999.

94. Carden A, Timlin JA, Morris MD, Hoffler, II CE, Kozloff K, Goldstein SA: Raman Imaging of Bone Mineral and Matrix: Composition and Function. Proc. S.P.I.E. 3608:132-138, 1999.

95. Richards M, Wineman AS, Alsberg E, Goulet JA, Goldstein SA: Viscoelastic Characterization of Mesenchymal Gap Tissue and Consequences for Tension Accumulation During Distraction. Journal of Biomechanical Engineering, 121:116-122, February, 1999.

96. Zysset PK, Ominsky MS, Goldstein SA: A Novel 3D Microstructural Model for Trabecular Bone: II. The Relationship Between Fabric and the Yield Surface. Computer Methods in Biomechanics and Biomedical Engineering, 1:1-11, 1999.

97. Steen H, Tseng K-F, Goldstein SA, Carpenter JE: Harvest of Patellar Tendon (Bone-Tendon-Bone) Autograft for ACL Reconstruction Significantly Alters Surface Strain in the Human Patella. Journal of Biomechanical Engineering, 121:229-233, April 1999.

98. Richards M, Waanders NA, Weiss JA, Bhatia V, Senunas LE, Schaffler MB, Goldstein SA, Goulet JA: Reduced Gap Strains Induce Changes In Bone Regeneration During Distraction. Journal of Biomechanical Engineering, 121:348-355, 1999.

99. Bonadio J, Smiley E, Patil P, Goldstein SA: Localized, Direct Plasmid-Gene Delivery In Vivo: Prolonged Therapy Results in Reproducible Tissue Regeneration. Nature Medicine, 5(7):753-759, 1999.

100. Zysset PK, Guo XE, Hoffler CE, Moore KE, Goldstein SA: Elastic Modulus and Hardness of Human Cortical and Trabecular Lamellae Measured by Nanoindentation. Journal of Biomechanics, 32(10):1005-1012, 1999.

101. Cody DD, Gross G, Hou F, Fyhrie D, Spencer HJ, Goldstein SA: Femoral Strength is Better Predicted by Finite Element Models than QCT and DXA. Journal of Biomechanics, 32(10):1013-1020, 1999.

102. Goldstein SA, Patil PV, Moalli MR: Perspectives on Tissue Engineering of Bone. Clinical Orthopaedics and Related Research, 367S:S419-S423, 1999.

103. Goldstein SA: Breakout Session 2: Bone, Clinical Orthopaedics and Related Research, 367S:S133-S134, 1999.

104. Richards M, Goulet JA, Schaffler MB, Goldstein SA: Temporal and Spatial Characterization of Regenerate Bone in the Lengthened Rabbit Tibia. Journal of Bone and Mineral Research, 14(11):1978-1986, 1999.

105. Labhasetwar V, Bonadio J, Goldstein SA, Levy RJ: Gene Transfection using Biodegradable Nanospheres: Results in Tissue Culture and a Rat Osteotomy Model. Colloids and Surfaces B: Biointerfaces, 16:281-290, 1999.

106. Richards M, Huibregtse BA, Caplan AI, Goulet JA, Goldstein SA: Marrow-Derived Progenitor Cell Injections Enhance Bone Regeneration During Distraction. Journal of Orthopaedic Research, 17(6):900-908, 1999.

107. Ciarelli TE, Fyhrie DP, Schaffler MB, Goldstein SA: Variations in Three-Dimensional Cancellous Bone Architecture of the Proximal Femur in Women with Hip Fractures and in Controls. Journal of Bone and Mineral Research, 15(1):32-40, 2000.

108. Elder SH, Kimura JH, Soslowsky LJ, Lavagnino M, Goldstein SA: Effect of Compressive Loading on Chondrocyte Differentiation in Agarose Cultures of Chick Limb-Bud Cells. Journal of Orthopaedic Research, 18(1):78-86, 2000.

109. Hankenson KD, Bain SD, Kyriakides TR, Smith EA, Goldstein SA, Bornstein P: Increased Marrow-Derived Osteoprogenitor Cells and Endosteal Bone Formation in Mice Lacking Thrombospondin 2. J Bone Min Res 15(5):851-862, 2000.

110. Richards M, Kozloff KM, Goulet JA, Goldstein SA: Increased Distraction Rates Influence Precursor Tissue Composition Without Affecting Bone Regeneration. J Bone Min Res 15(5):982-989, 2000.

111. Guo XE, Goldstein SA: Vertebral Trabecular Bone Microscopic Tissue Elastic Molulus and Hardness Do Not Change in Ovariectomized Rats. J Orthop Res 18(2):333-336, 2000.

112. Smith E, Frankenburg E, Goldstein S, Koshizuka K, Elstner E, Said J, Kubota T, Uskokovic M, Koeffler HP: Effect of Long-Term Administration of Vitamin D3 Analogs to Mice, Journal of Endocrinology 165:163-172, 2000.

113. Ozaki W, Buchman SR, Goldstein SA, Fyhrie DP: A Comparative Analysis of the Microarchitecture of Cortical Membranous and Cortical Endochondral Onlay Bone Grafts in the Craniofacial Skeleton. Plastic and Reconstructive Surgery 104(1):139-147, 1999.

114. Hoffler, CE, Moore KE, Kozloff K, Zysset PK, Brown MB, Goldstein SA: Heterogeneity of Bone Lamellar-Level Elastic Moduli. BONE, 26(6):603-609, June 2000.

115. Moalli MR, Caldwell NJ, Patil PV, Goldstein SA: An In Vivo Model for Investigations of Mechanical Signal Transduction in Trabecular Bone. J Bone Min Res 15(7):1346-1353, 2000.

116. Hoffler CE, Moore KE, Kozloff K, Zysset PK, Goldstein SA: Age, Gender and Bone Lamellae Elastic Moduli. J Orthop Res, 18:432-437, 2000.

117. Loder RT, Hernandez MJ, Lerner AL, Winebrener DJ, Goldstein SA, Hensinger, RN, Liu C-Y, Schork MA: The Induction of Congenital Spinal Deformities in Mice by Maternal Carbon Monoxide Exposure. Journal of Pediatric Orthopaedics, 20:662-666, 2000.

118. Elder S, Frankenburg E, Goulet JA, Yetkinler D, Poser R, Goldstein SA: Biomechanical Evaluation of Calcium Phosphate Cement-Augmented Fixation of Unstable Intertrochanteric Fractures. Journal of Orthopaedic Trauma, 14(6):386-393, 2000.

119. Goldstein, SA: In Vivo Nonviral Delivery Factors to Enhance Bone Repair. CORR 379S:S113-S119, 2000

120. McCreadie BR, Goldstein SA: Perspective: Biomechanics of Fracture: Is Bone Mineral Density Sufficient to Assess Risk. J Bone Miner Res 15(12): 2305-2308, 2000.

121. Butler DL, Goldstein SA, Guilak F: Functional Tissue Engineering: The Role of Biomechanics. J Biomech Eng 122:570-575, 2000.

Articles Accepted for Publication:

122. Waanders, NA, Kuhn, JL, Fowlkes, JB, Herzenberg, JE, Goldstein, SA, Goulet, JA: A Morphologic Study of New Bone Structure in the Early Stages of Distraction Osteogenesis. Bone, (in press).

123. Guo XE, Zysset PK, Hoffler CE, Moore KE, Goldstein SA: An Application of Nanoindentation Technique to Measure Microscopic Bone Tissue Properties. Journal of Biomechanical Engineering, (in press).

Articles Submitted for Publication

1. Ko C-C, Kohn DH, Hollister SJ, Goldstein SA: A Relationship Between Tissue Strain and Amount of Osseointegrated Bone for TI Porous Coated Implants. Journal of Biomechanics, (submitted).

2. Cody, DD, Gross, GJ, Spencer, HJ, Goldstein, SA: Femur Density and Geometry Predict Strength Ex-Vivo. Journal of Bone and Mineral Research, (submitted).

3. Dedrick DK, Widmer WR, O'Connor B, Goulet RW, Visco DM, Brandt KP, Albrecht M, Goldstein SA: Evaluation of Subchondral Trabecular Bone in Experimentally Induced Canine Osteoarthritis With and Without Massive Differentiation. Arthritis and Rheumatism 1998 (submitted).

4. Sherick D, Buchman SR, Goulet RW, Goldstein SA: A New Method for the Quantitative Analysis of Cranial Suture Biology, Cleft Palate-Craniofacial Journal (submitted).

5. Elder SH, Goldstein SA, Kimura JH, Soslowsky LJ, Spengler DM: Chondrocyte Differentiation is Modulated by Frequency and Duration of Cyclic Compressive Loading. Journal of Biomechanics, (submitted).

6. Ciarelli TE, Schaffler MB, Goldstein SA: Age Effects on the Fatigue Behavior of Human Vertebral Cancellous Bone Tissue. J Orthop Res (submitted, 2000).

7. McCreadie BR, Champion JA, Goldstein SA: Trabecular Bone Tissue Mineral Content in Osteoporotic and Normal Women. J Bone Min Res (submitted).

8. Guilak F., Butler DL, Goldstein SA: Functional Tissue Engineering: The Role of Biomechanics in Articular Cartilage Repair. Submitted.

Books

1. Goldstein SA (ed): Advances in Bioengineering, 1991 ASME Press, New York, NY.

2. Carlson DS, Goldstein SA (eds): Bone Biodynamics in Orthodontic and Orthopaedic Treatment, Vol. 27 Craniofacial Growth Series, 1991.

Chapters in Books

1. Matthews LS, Goldstein SA: A New Prosthesis Interface Surface Geometry: Provision for Initial Stability and Graduate Bone Stress Distribution. Total Knee Arthroplasty: Proceedings of the Knee Society, 1985-86. Aspen Publishers, 1987, Rockville, Maryland, pp. 121-129.

2. Matthews LS, Kaplan SI, Kaufer H, Goldstein SA: The Role of Long-Stemmed Patellofemoral Spherocentric Arthroplasty in the Treatment of Patients with Severe Damage to the Knee Joint. In Total Knee Arthroplasty: Proceedings of the Knee Society, 1985-86. Aspen Publishers, 1987, Rockville, Maryland, pp. 286-295.

3. Goldstein SA, Hollister SJ, Kuhn JL, Kikuchi N: The Mechanical and Remodeling Properties of Trabecular Bone. In Biomechanics of Diarthrodial Joints - Vol. II pg. 61-81, Ed. V.C. Mow, A. Ratcliffe, S.L. Woo, 1990.

4. Bonadio J, Goldstein SA: The Inherited Connective Tissue Disorders of the Vascular Wall. In Molecular Biology of the Cardiovascular System, R. Roberts, ed., Blackwell Scientific Publications, Cambridge, MA, 1991.

5. Goldstein SA: Clinical Applications of Bone Remodeling Dynamics in Bone Biodynamics in Orthodontic and Orthopaedic Treatment, Vol. 27 Craniofacial Growth Series (eds) D Carlson, SA Goldstein, 1991.

6. Goldstein SA, Frankenburg E, Kuhn JL: Biomechanics of Bone. In: Accidental Injury: Biomechanics and Prevention. In. Nahum and Levin (eds). Springer-Verlage New York; New York, New York, 1993.

7. Bonadio J, Goldstein SA: Our Understanding of Inherited Skeletal Fragility and What This Has Taught Us About Bone Structure and Function. In: Cellular and Molecular Biology of the Bone; G. Noda (ed). Academic Press, Inc. San Diego, CA., pp. 169-189, 1993.

8. Matthews LS, Goldstein SA: Orthopaedic Surgery. In: Surgery: Scientific Principles and Practice (eds) L.J. Greenfield, M.W. Mulholland, K.T. Oldham, G.B. Zelenock; Lippincott Publishers, Philadelphia, PA, 1993.

9. Wong M, Germiller J, Bonadio J, Goldstein SA: Neuromuscular Atrophy Alters Collagen Gene Expression, Pattern Formation, and Mechanical Integrity of the Chick Embryo Long Bone. In Limb Development and Regeneration. John Wiley & Sons, Inc., New York, New York, 1993.

10. Goldstein, SA, Waanders, N, Guldberg, RE, Steen H, Senunas L, Goulet, JA, Bonadio J: Stress Morphology Relationships During Distraction Osteogenesis: Linkages Between Mechanical and Architectural Factors in Molecular Regulation. Bone Formation and Repair, AAOS Symposium, ed. C.T. Brighton, G.E. Friedlaender, J.M. Lane, pp. 405-419, 1994.

11. Kuhn JL, Goldstein SA: The Mechanical Properties of the Growth Plate and its Response to Mechanical Stimuli, Ch. 5. In Orthopaedic Basic Science; SR Simon (ed). AAOS, pp. 185-217, 1994.

12. Hollister, SJ, Goldstein, SA: Relationships Between Trabecular Tissue Strains and Bone Adaptation under Controlled Implant Loads. In Bone Structure and Remodeling, World Congress of Biomechanics Symposium on Trabecular Bone, ed. A Odgaard, H Weinans, pp. 51-64, 1995.

13. Matthews LS, Goldstein SA: Orthopaedic Surgery, In, L.J. Greenfield, M.W. Mulholland, K.T. Oldham, G.B. Zelenock, K.D. Lillemoe (Ed.), Surgery: Scientific Principles and Practices: 2nd Edition, Lippincott-Raven, Section P, Chapter 106, 2141-2152, 1997.

14. Hoffler CE, McCreadie BR, Smith EA, Goldstein SA: A Hierarchical Approach to Exploring Bone Mechanical Properties. In Mechanical Testing of Bone and the Bone-Implant Interface, Y.H. An, R.A. Draughn (Eds.), CRC Press, Boca Raton, FL, Chapter 8, 133-149, 2000.

15. McCreadie, BR, Goulet RW, Feldkamp LA, Goldstein SA: Hierarchical Structure of Bone and Micro-Computed Tomography. In Non-invasive Assessment of Trabecular Bone Architecture and the Competence of Bone, S Majumdar and BK Bay (Eds), Kluwer Academic/Plenum Publishers, New York. (In press)

16. Evans CH, Goldstein SA, Robbins PD, Baltzer AWA, Lieberman J: Gene Therapy for Bone Regeneration and Repair. In Bone Regeneration and Repair: Biology and Clinical Applications. Humana Press, (in press).

Abstracts

1. Goldstein, SA, Wilson, D, Matthews, LS, Sonstegard, DA: An Experimental Determination of Numerical Values for Elastic Modulus and Ultimate Strength of Human Tibial Trabecular Bone as a Function of Location. Ortho Trans., 4:192, 1980.

2. Armstrong, TJ, Castelli, M, Evans, G, Goldstein, SA: A Study of Histological Effects of Cumulative Trauma to Tissues Inside the Carpal Tunnel. J. Biomechanics, 14:491, 1981.

3. Goldstein, SA, Armstrong, TJ, Chaffin, DB: A Model of Cumulative Trauma in Tendon and Tendon Sheath Disorders. J. Biomechanics, 14:487, 1981.

4. Goldstein, SA, Armstrong, TJ, Chaffin, DB, Matthews, LS: Cumulative Strain in Tendonous Tissues in Response to Physiologic Loads. J. Biomechanics, 15(4):338, 1982.

5. DeVito, P, Rivlin, M, Price, D, Goldstein, SA, Matthews, LS: Friction Major Factor in Plate and Screw Fracture Fixation Stability. Ortho. Trans., 6(2):279, 1982.

6. Matthews, LS, Reschly, R, Coale, NE, Goldstein, SA: A Detailed Study of the Effects of Long-Term Use on a Total Knee Prosthesis. Trans. Orthop. Research Society, 7:301, 1982.

7. Zand, M, Goldstein, SA, Matthews, LS: Fatigue Failure of Cortical Bone Screws: A New Screw Design. Trans. Orthop. Research Society, 7:300, 1982.

8. Goldstein, SA, Armstrong, TJ, Chaffin, DB, Matthews, LS: Biomechanical Aspects of Cumulative Trauma to Collagenous Tissues. Orthop. Trans., 6(2):217, 1982.

9. Goldstein, SA, Matthews, LS, Braunstein, E, Marks, B: The Distribution of Tibial Trabecular Bone as Determined by Computer-Assisted Tomography. Trans. Orthop. Research Society, 7:302, 1982.

10. Goldstein, SA, Louis, DS, Greene, TL, Jacobson, KE, Rasmussen, C, Kolowich, P: An Evaluation of Normal Guides for the Variations Between Stationary and Moving Two-Point Discrimination. Orthop. Trans., 7(1):44 1982.

11. Matthews, LS, Kaplan, DE, Goldstein SA, Kaufer, H: Prosthetic Arthroplasty for Gross Functional Metaphyseal Bone Loss: The Use of a Long-Stem Prosthesis. Orthop. Tran., 6(3):334, 1982.

12. Coale, EH, Goldstein, SA, Reschly, RR, Matthews, LS: A Detailed Study of the Effects of Long-Term Use on a Total Knee Prosthesis. J. Biomechanics, 16(4):284, 1983.

13. Goldstein, SA, Matthews, LS, Braunstein, EM, Marks, B: The Distribution of Tibial Trabecular Bone Properties Using Computed Axial Tomography. J. Biomechanics, 16(4):295, 1983.

14. Louis, DS, Greene, TL, Jacobson, KE, Rasmussen, C, Kolowich, P, Goldstein, SA: An Evaluation of Normal Guides for the Variations Between Stationary and Moving Two-Point Discrimination. Ortho. Trans., 7(1):43-44, 1983.

15. Louis, DS, Jacobson, KE, Rasmussen, CJ, Greene, TL, Goldstein, SA: An Evaluation of Normal Guides for the Variations Between Stationary and Moving Two-Point Discrimination. International Federation of Societies for Surgery of the Hand, Abstract Book, pp. 48-49, October 1983.

16. Hankin, FM, Campbell, SE, Goldstein, SA, Matthews, LS: Hydrogen Peroxide as a Topical Hemostatic Agent. Ortho. Trans., 7(3):428, 1983.

17. Matthews, LS, Malvitz, TA, Goldstein, SA, Kaufer, H, Katz, B: Proximal Tibial Osteotomy: A Long-Term Clinical Follow Up. Ortho. Trans., 7(3):385, l983.

18. Goldstein, SA, Matthews, LS, Braunstein, EM, Marks, BW: Computed Tomographic Analysis of Biomechanical Properties of the Tibia. Radiology l49(P):234, 1983.

19. Goldstein, SA, Weiss, A-PC, Coale, E, Matthews, LS: Surface Strain Studies of the Human Patella. Ortho. Trans., 8(2):232-233, 1984.

20. Goldstein, SA, Greene, TL, Ward, WS, Matthews, LS: A Biomechanical Evaluation of the Function of the Digital Pulleys. Ortho. Trans., 8(2):354, l984.

21. Matthews, LS, Goldstein, SA, Malvitz, TA, Katz, B: Proximal Tibial Osteotomy: How Long Does It Delay Total Knee Arthroplasty? Ortho. Trans., 8(3):376, 1984.

22. Smith, PA, Ku, JL, Goldstein, SA, Matthews, LS: A Biomechanical Study of Autoclaved Autogenous Bone. Ortho. Trans., 8(3):495, 1984.

23. Goldstein, SA, Weiss, A-PC., Kasman, R, Matthews, LS: Surface Strain Studies of the Human Patella. J. Biomechanics, 17(11):868, 1984.

24. Dickie, DL, Goldstein, SA, Flynn, MJ, Bridges, P: Analysis of the Geometric Properties of Human Long Bones Using Computer Axial Tomography. J. Biomechanics, l7(l):868, 1984.

25. Braunstein, EM, Goldstein, SA, Ku, JL, Smith, PA, Matthews, LS: Computed Tomography and Plain Radiography in Upper Extremity Fracture Healing. Radiology, 157(P):176, 1985.

26. Ku, JL, Smith, PA, Goldstein, SA, Matthews, LS: An Experimental Investigation of the Fate of Autogenous Autoclaved Bone Grafts. Ortho. Trans., 9(2):340, 1985.

27. Matthews, LS, Goldstein, SA, Ku, JL, Carpenter, J: Prosthesis Interface Surface Geometry: Provision for Initial Stability and Graduated Bone Stress Distribution. Ortho. Trans., 9(2):289, 1985.

28. Wojtys, EM, Redfern, MS, Trier, EM, Matthews, LS, Goldstein, SA: A Computer Assisted System for Simultaneous Evaluation of Multiple Mechanical Factors of Knee Joint Stability: The Lenox-Hill Brace. Ortho Trans., 9(2):310, l985.

29. Goldstein, SA, Ku, JL, Kayner, DC, Matthews, LS: An Experimental Model for Inducing Trabecular Bone Remodeling. Ortho. Trans., 9(2):304, 1985.

30. Ku, JL, Smith, PA, Goldstein, SA, Matthews, LS: An Experimental Investigation of the Fate of Autogenous Autoclaved Bone Grafts. Orthop. Trans., 9(2):340, 1985.

31. Goldstein, SA, Greene, TL, Louis DS, Ward, WS, Matthews, LS: A Biomechanical Evaluation of the Function of the Digital Pulleys. J. Biomechanics, 18(3):231, 1985.

32. Matthews, LS, Kaplan, SI, Kaufer, H, Goldstein, SA: The Role of Long Stemmed Patellofemoral Spherocentric Arthroplasty in the Treatment of Patients with Severe Damage to the Knee Joint. Ortho. Trans., 10(l):170, 1986.

33. Ciarelli, MJ, Goldstein, SA, Dickie, D, Ku, JL, Kapper, M, Stanley, J, Flynn, MJ, Matthews, LS: Experimental Determination of the Orthogonal Mechanical Properties, Density, and Distribution of Human Trabecular Bone from the Major Metaphyseal Regions Utilizing Materials Testing and Computed Tomography. Ortho. Trans., 10(2):238, 1986.

34. Bylski, DI, Goldstein, SA, Kayner, DC, Matthews, LS: Experimental Determination of Meniscal Mechanics in Intact Knee Joints. Ortho. Trans., 10(2):238, 1986.

35. Goldstein SA, Ku JL, Hollister S, Kayner DC, Matthews LS: The Effects of Applied Stress on Experimentally Controlled Remodeling in Trabecular Bone. Ortho Trans, 10(2):318, 1986.

36. Hollister, SJ, Goldstein, SA, Ku, JL, Matthews, LS: An Experimental Evaluation of the Relationship Between Strain Energy Density and Trabecular Bone Remodeling. Ortho. Trans., 10(2):318, 1986.

37. Matthews, LS, Goldstein, SA, Benedict, W, Shan, A: A New Transducer for Measuring Pressures Within Tissue Compartments. Ortho. Trans., 10(2):378, 1986.

38. Goldstein SA, Feldkamp LA, Ku JL, Champlain FW, Zand M, Jesion G, Ciarelli M, Matthews LS: Architectural Effects on Trabecular Bone Material Properties. Ortho Trans, 10(2):396, 1986.

39. Goldstein, SA, Ku, JL, Kayner, DC, Hollister, S, Matthews, LS: Trabecular Bone Remodeling. J. Biomechanics, 19(6):473, 1986.

40. Ciarelli, M, Peterson, J, Macintosh, B, Ku, JL, Matthews, LS, Goldstein, SA: The Orthogonal Material Properties of Trabecular Bone: Correlation with Computed Tomography Density Measurements. J. Biomechanics, 19(6):475, 1986.

41. Haughton, J, Drake, K, Bylski, D, Matthews, LS, Goldstein, SA: A New Dynamic Pressure Transducer. J. Biomechanics, 19(6):475, 1986.

42. Ku, JL, Goldstein, SA, Axelrod, D, Matthews, LS: A Method for Measuring Surface Strains from Individual Trabeculae. J. Biomechanics, 19(6):475, 1986.

43. Goldstein, SA, Ku, JL, Kayner, DC, Hollister, S, Matthews, LS: Trabecular Bone Remodeling. J. Biomechanics, 19(6):473, 1986.

44. Wojtys, EM, Goldstein, SA, Redfern, M, Trier, E, Matthews, LS: Biomechanical Evaluation of the Lenox-Hill Knee Brace. Ortho. Trans., 10(3):479-480, Fall 1986.

45. Ku, JL, Goldstein, SA, Choi, K, London, M, Herzig, M, Matthews, LS: The Mechanical Properties of Single Trabeculae. Trans. Ortho. Res. Soc., 12:48, 1987.

46. Struhl, S, Goldstein, SA, Dickie, D, Flynn, MJ, Matthews, LS: The Distribution of Mechanical Properties of Trabecular Bone Within Vertebral Bodies and Iliac Crests. Trans. Ortho. Res. Soc., 12:262, 1987.

47. Ciarelli, MJ, Bylski, D, Goldstein, SA, Gordon, JD, Wojtys, EM, Matthews, LS: Effects of Partial Meniscectomy and Ligament Resection of Meniscal Displacement and Strain Patterns in Cadaver Knees. Trans. Ortho. Res. Soc., 12:468, 1987.

48. Dickie, DL, Goldstein, SA, Flynn, MJ, Ge, Z, Kleerekoper, M: Regional Vertebral Bone Density Distribution Measurements and Their Correlation to Whole Bone Strength. Trans. Ortho. Res. Soc., 12:261, 1987.

49. Goldstein SA Ku JL, Hollister SJ, Goulet RW, Champlain F, Matthews LS: Experimentally Controlled Trabecular Bone Remodeling: Effects of Applied Stress. Trans Ortho Res Soc 12:461, 1987.

50. Kaufer, H, Matthews, LS, Goldstein, SA: The Long-Stem Spherocentric Knee Prosthesis for Revision of Failed Total Knee Arthroplasty. Ortho. Trans., 11(1):168-169, Spring 1987.

51. Struhl, S, DeClaire, JD, Goldstein, SA, Kaufer, H: Long Term Follow-Up of Total Hip Arthroplasty in Patients Under Age 35. Ortho. Trans., 11(3):449, Fall 1987.

52. Goulet, RW, Ciarelli, MJ, Goldstein, SA, Kuhn, JL, Feldkamp, LA, Kruger, D, Viviano, D, Champlain, F, Matthews, LS: The Effects of Architecture and Morphology on the Mechanical Properties of Trabeculae Bone. Trans. of Ortho. Res. Soc., l3:73, l988.

53. Kuhn, JL, Choi, KW, Goldstein, SA, Ciarelli, MJ, Matthews, LS: The Limitations of Canine Trabecular Bone as a Model for Human Trabecular Bone: A Biomechanical Study. Trans. of Ortho. Res. Soc., 13:78, 1988.

54. Goldstein, SA, Kuhn, JL, Hollister, SJ, Goulet, RW, Loubert, PV, Sweet, K, Matthews, LS: The Relationship Between Experimentally Controlled Loads and Trabecular Bone Remodeling. Trans. of Ortho. Res. Soc., 13:102, 1988.

55. Hollister, SJ, Goldstein, SA, Kuhn, JL, Matthews, LS: Correlation of Finite Element Stress Predictions with Trabecular Bone Remodeling In Vivo: Effects of Mesh Refinement and Mechanical Property Assumptions. Trans. of Ortho. Res. Soc., 13:233, 1988.

56. Dickie DL, Goldstein SA, Flynn MJ, Ge ZF, Matthews LS: Vertebral rBMD Distribution and Fracture Characteristics: In Vitro and In Vivo Results. Trans of Ortho Res Soc, 13:368, 1988.

57. Kruger, DM, Hak, DJ, Viviano, DM, Goldstein, SA, Herzenberg, JE: Biomechanical Comparison of Single and Double Steinmann Pin Fixation for Slipped Capital Femoral Epiphysis. Trans. of Ortho. Res. Soc., 13:407, 1988.

58. Goldstein SA: Traction Force Profiles Associated with the Use of a Fracture Table. Trans of Ortho Res Soc 13:445, 1988.

59. Layton, MW, Goldstein, SA, Goulet, RW, Feldkamp, LA., Bole, GG: Evaluation of Subchondral Bone Architecture in Experimental Osteoarthrosis by Microscopic Computerized Axial Tomography. Trans. of Ortho. Res. Soc., 13:489, 1988.

60. Goldstein, SA, Matthews, LS, Sweet, KA, Samson, S, Choi, K: Evaluation of a New Prosthesis Interface Surface Geometry. J. Biomechanics, 21(10):852, 1988.

61. Kuhn, JL, Goulet, RW, Goldstein, SA, Feldkamp, LA: A Study of the Variation of Trabecular Architectures in Small Volumes of Bone Using a Microcomputed Tomography System. J. Biomechanics, 21(10):853, 1988.

62. Chaffin, DB, Redfern, MS, Goldstein, SA: Lumbar Muscle Moment Arm Lengths from CT Scans of 96 Women. J. Biomechanics, 21(10):854, 1988.

63. Goulet, RW, Ciarelli, MJ, Goldstein, SA, Kuhn, JL, Feldkamp, LA, Kruger, D.M., Viviano, D, Champlain, F, Matthews, LS: The Effects of Architecture and Morphology on the Mechanical Properties of Trabecular Bone. Orthop. Trans., 12(2): 332, 1988.

64. Kuhn JL, Choi K, Goldstein SA, Ciarelli MJ, Matthews LS: The Limitations of Canine Trabecular Bone as a Model for Human Trabecular Bone: A Biomechanical Study. Orthop Trans 12(2): 334, 1988.

65. Goldstein, .SA, Kuhn, JL, Hollister, SJ, Goulet, RW, Loubert, PV, Sweet, KA, Matthews, LS: The Relationship Between Experimentally Controlled Loads and Trabecular Bone Remodeling. Orthop. Trans., 12(2): 345, 1988.

66. Layton, MW, Goldstein, SA, Goulet, RW, Feldkamp, LA, Bole, GG: Evaluation of Subchondral Bone Architecture in Experimental Osteoarthrosis by Microscopic Computerized Axial Tomography. Orthop. Trans., 12(2): 399, 1988.

67. Hollister, SJ, Goldstein, SA, Kuhn, JL, Matthews, LS: Correlation of Finite Element Stress Predictions with Trabecular Bone Remodeling In Vivo: Effects of Mesh Refinement and Mechanical Property Assumptions. Orthop. Trans., 12(2): 458 1988.

68. Dickie DL, Goldstein SA, Flynn MJ, Ge ZF, Matthews LS: Vertebral rBMD Distribution and Fracture Characteristics: In Vitro and In Vivo Results. Orthop Trans 12(2): 470, 1988.

69. Kruger, DM, Hak, DJ, Viviano, DM, Goldstein, SA, Herzenberg, JE: Biomechanical Comparison of Single and Double Steinmann Pin Fixation for Slipped Capital Femoral Epiphysis. Orthop. Trans., 12(2): 485, 1988.

70. Kruger DM, Kayner DC, Hankin FM, Falahee MH, Kaufer H, Matthews LS, Goldstein SA: Traction Force Profiles Associated with the Use of a Fracture Table. Orthop Trans 12(2): 497, 1988.

71. Matthews, LS, Goldstein, SA: A New Prosthesis Surface Interface Geometry that Provides Initial Stability and Graduated Bone Stress Distribution. Orthop. Trans., 12(3): 553, 1988.

72. Kruger DM, Hak DJ, Goldstein SA, Viviano DM, Herzenberg JE: Single vs Double Pin Fixation for Acute Slipped Capital Femoral Epiphysis (SCFE). Orthop Trans, 12(3):563, 1988.

73. Bueche MJ, Phillips WA, Goldstein SA, Gordon J, Best R: The Effect of Interposition Material on Mechanical Behavior in Partial Physeal Resection-A Canine Model. Orthop Trans 12(3):574, 1988.

74. Choi, K, Kuhn, JL, Ciarelli, MJ, Goldstein, SA: The Elastic Modulus of Trabecular, Subchondral, and Cortical Bone Tissue. Trans. Ortho. Res. Soc., 14:102, 1989.

75. Smith, MD, Cody, DD, Goldstein, SA, Matthews, LS: Regional Bone Density of the Proximal Femur and Biomechanical Properties. Trans. of Ortho. Res. Soc., 14:105, 1989.

76. Loubert, PV, Wojtys, EM, Viviano, DM, Samson, SY, Goldstein, SA: A Quantitative Assessment of the Efficacy of 14 Functional Knee Braces. Trans. Ortho. Res. Soc., 14:221, 1989.

77. Viviano, DM, Goldstein, SA, Loubert, PV, Matthews, LS: The Effects of Experimentally Controlled Load on Trabecular Bone Ingrowth. Trans. Ortho. Res. Soc., 14:261, 1989.

78. Goulet, RW, Feldkamp, LA, Kubinski, DJ, Goldstein, SA: Predicting the Architectural Orientation of Trabecular Bone. Trans. Ortho. Res. Soc., 14:263, 1989.

79. Hollister SJ. Fyhrie DP, Jepsen KJ, Goldstein SA: A New Procedure for Calculating Apparent Bone Properties and Tissue Micro-Stresses Using Homogenization Theory. Trans Ortho Res Soc, 14:266, 1989.

80. Hollister, S., Fyhrie, DP, Jepsen, KJ, Goldstein, SA: An Analysis of Trabecular Bone Micro-Mechanics Using Homogenization Theory With Comparison to Experimental Results. Trans. XII Congress, International Society of Biomechanics, 22(10):1014, 1989

81. Fyhrie, DP, Jepsen, KJ, Hollister, SJ, Goldstein, SA: Predicting Trabecular Bone Strength and Micro-Strain Using Homogenization Theory. Trans XII Congress, International Society of Biomechanics, 22(10):1025, 1989

82. Hollister, SJ, Goldstein, SA, Jepsen, KJ, Goulet, RW: Continuum and Microstructural Stress Morphology Relationships for Trabecular Bone Subject to Controlled Implant Loads. Trans. Orthop. Res. Soc., 15(1):74, 1990.

83. Goldstein SA, Korotko JR, Lynch W, D'Alecy SL, Huston L, Weigand KE: The Effect of Zeolite A on the Mechanical Properties of Rat Bone after Ovariectomy. Trans Orthop Res Soc 15(1):52, 1990.

84. McCubbrey, DA, Cody, DD, Kuhn, JL, Goldstein, SA, Flynn, MJ : Static and Fatigue Failure Properties of Thoracic and Lumbar Vertebral Bodies and Their Relation to Regional Density. Trans. Orthop. Res. Soc., 15(1):178, 1990.

85. Tsai, E, Jepsen, KJ, Kuhn, JL, Bonadio, JF, Goldstein, SA: A Transgenic Mouse Model of Osteogenesis Imperfecta Type I. Trans. Orthop. Res. Soc., 15(2):564, 1990.

86. Choi, K, Kuhn, JL, Goldstein, SA: Micro Mechanical Properties of Human Trabecular Bone Tissue. Trans. First World Congress of Biomechanics. Vol II:131, 1990.

87. Ciarelli, MJ, Kuhn, JL, Mansoura, MK, Goldstein, SA: The Compressive Properties of Growth Plate Cartilage. Trans. First World Congress of Biomechanics. Vol. II:268, 1990.

88. McCubbrey DA, Goulet RW, Goldstein SA, Shulick AM: Vertebral Body Architecture and Mechanical Properties Alterations Due to Ovariectomy in the Beagles. Trans Orthop Res Soc 16(1):284, 1991.

89. Jepsen KJ, Mansoura MK, Bonadio J, Kuhn JL, Goldstein SA: The Adaptational Response of Cortical Bone to Defective Type I Collagen Synthesis. Trans Orthop Res Soc 16(1):30, 1991.

90. Goldstein SA, Matthews LS, Choi K, Jepsen KJ, Shulick AM: The Effect of Prosthesis Surface Geometry on Implant Stability and Tissue Ingrowth. Trans. Orthop Res Soc 16(1):92, 1991.

91. Hollister, SJ, Kikuchi, N, Goldstein, SA: Effects of Implant Interface Design on Bone Ingrowth Predicted Using Topology Optimization. Trans. Orthop. Res. Soc. 16(1):108, 1991.

92. Mason, DJ, Goulet, JA, Rouleau, JP, Goldstein, SA: Comminuted Posterior Wall Fractures Of the Acetabulum: A Study of Fixation Stability. Trans. Orthop. Res. Soc. 16(1):144, 1991.

93. Dedrick, DK, Goulet, RW, Widmer, WR, O'Conner, BL, Brandt, KD, Albrecht, M, Goldstein, SA: Evaluation of Trabecular Bone in Experimentally Induced Canine Osteoarthritis. Trans. Orthop. Res. Soc. 16(2):332, 1991.

94. Ciarelli, MJ, Kuhn, JL, Goldstein, SA: Viscoelastic Studies on Growth Plate Cartilage. Trans. Orthop. Res. Soc. 16(2):363, 1991.

95. Lynch WR, Goldstein SA, Shulick AM, Mase CA: The Effects of Calcitonin on Torsional Properties of The Long Bones of Ovariohysterectomized Beagles. Trans. Orthop Res Soc 16(2):430, 1991.

96. Choi, K, Goldstein, SA: The Fatigue Properties of Bone Tissues on a Microstructural Level. Trans. Orthop. Res. Soc. 16(2):485, 1991.

97. Goldstein SA, Hollister SJ, Kuhn J., Bonadio JF, Matthews L.S.: Mechanical Influences on Bone Adaptation. 1991 Adv. in Bioeng 20:311, 1991.

98. McCubbrey DA, Goldstein SA, Cody DD, Goulet RW, Kuhn, JL: The Regional Density, Architectural, and Tissue Properties of Vertebral Trabecular Bone and Their Relation to Whole Bone Failure Properties. 1991 Adv. in Bioeng 20:575, 1991.

99. Wong M, Bonadio J, Goldstein SA: The Effect of Reduced Mechanical Loading on the Growth and Morphogenesis of the Chick Embryo Long Bone. Trans. Orthop. Res. Soc. 17(1):183, 1992.

100. Goulet RW, Feldkamp LA, Goldstein SA: Quantification of the Architecture of Cancellous Bone by Surface and Volume Orientation Methods. Trans. Orthop. Res. Soc. 17(1):159, 1992.

101. Jepsen KJ, Mansoura MK, Kuhn JL, Wu H, Jaenisch R, Bonadio JF, Goldstein SA: An In Vivo Assessment of the Contribution of Type 1 Collagen to the Mechanical Properties of Cortical Bone. Trans Orthop Res Soc 17(1):93, 1992.

102. Wong M, Lawton T, Goetinck PF, Goldstein SA, Bonadio J: The Contribution of Aggrecan to the Functional Properties of Membranous Bone of the Chick Embryo. Trans Orthop Res Soc 17(1):27, 1992.

103. Hollister, SJ, Goldstein, SA: Trabecular Tissue Strain Estimates for Bone Adapted to Controlled Implant Loads. Trans. BED 24: 254-255, 1993.

104. McCubbrey, DA, Cody DD, Peterson EL, Flynn MJ, Goldstein SA: Predictive Models of Vertebral Static and Fatigue Failure Properties Using Regional Density. Trans. BED 24: 658-660, 1993.

105. Germiller, JA, Wong M, Bonadio JF, Goldstein SA: A Surgical Denervation Model Suggests a Role for Muscular Activity in the Development of Chick Embryo Long Bone. Trans. BED 24: 2, 1993: 661-664, 1993.

106. Jepsen KJ, Goldstein SA, Kuhn JL, Bonadio J, Gibson G, Schaffler MB: The Brittleness of Murine Cortical Bone: Dependence on Tissue Composition. Trans. BED 24: 2, 1993: 666-668, 1993.

107. Hollister SJ, Goldstein SA: Relationship of Trabecular Tissue Strain Alterations to Bone Adaptation under Controlled Implant Loads. Trans. BED 26:, 1993: 145-148, 1993.

108. Jepsen KJ, Schaffler MB, Goldstein SA: The Brittleness of Murine Cortical Bone: Dependence on Tissue Porosity. Trans. BED 26:, 1993: 307-309, 1993.

109. McCubbrey DA, Yian EH, Goulet RW, Shih M-S, Parfitt AM, Goldstein SA: The Effects of Calcitonin on Trabecular Bone Properties in the Ovariectomized Beagle. Trans Orthop Res Soc 18(1):53, 1993.

110. Germiller JA, Wong M, Bonadio JF, Goldstein SA: Effect of Muscular Atrophy on Extracellular Matrix Gene Expression in Developing Long Bone. Trans Orthop Res Soc 18(1):148, 1993.

111. Demetropoulos CK, Willis CB, Goldstein SA: Biomechanical Characteristics of Rat Trabecular Bone. Trans Orthop Res Soc 18(2):585, 1993.

112. Tseng K-F, Bonadio FJ, Stewart TA, Goldstein SA: The Effects of Local Expression of Growth Hormone on the Growth and Mechanical Properties of Murine Cortical Bone. Trans Orthop Res Soc 19(1): 45, 1994.

113. McCubbrey DA, Mascha EJ, Goulet RW, Goldstein SA: Relationships Between Trabecular Architecture and Failure Properties of Whole Vertebrae in the Beagle. Trans Orthop Res Soc 19(1): 55, 1994.

114. Frankenburg EP, Goldstein SA, Harris SA, Toomajian LR, Pellizzon GG, Bakker DA, Bauer TW: Evaluation of an In Situ-Setting Calcium Phosphate Grout in an In Vivo Canine Metaphyseal Defect Model. Trans Orthop Res Soc 19(1): 157, 1994.

115. Riemer BA, Eadie JS, Weissman DE, Haut KM, Hollister SJ, Goldstein SA: Characterization of the Architecture, Tissue Properties, and Continuum Behavior of Aging Trabecular Bone. Trans Orthop Res Soc 19(1): 189, 1994.

116. Waanders NA, Senunas LE, Steen H, Goulet JA, Bonadio J, Goldstein SA: Bone Formation in Distraction Osteogenesis Histologic and Immunohistochemical Findings. Trans Orthop Res Soc 19(1): 231, 1994.

117. Jepsen KJ, Schaffler MB, Gibson GJ, Bonadio J, Goldstein SA: Type I Collagen Mutation Leas to Altered Structure, Composition, and Mechanical Function in MOV13 Long Bone. Trans Orthop Res Soc 19(2): 341, 1994.

120. Guldberg RE and Goldstein SA: Reparative Osteogenesis in a Large-Volume Trabecular Bone Chamber. Trans Orthop Res Soc 19(2): 500, 1994.

121. Yin W, Rouleau J, Goldstein SA, Bonadio J: Molecular cloning of a Novel Fibrillin-Like cDNA: Expression In Callus Tissue as Alternatively Spliced Transcripts. Trans Orthop Res Soc 19(2): 509, 1994.

122. Frankenburg EP, Goldstein SA, Harris SA, Toomajian, Pellizzon GG, Rouleau JP: The Effects of Zeolite-A on Fracture Healing in a Rat Femoral Fracture Model. Trans Orthop Res Soc 19(2): 513, 1994.

123. Waanders NA, Steen H, Zanecki EM, Goulet JA, Goldstein SA: Evaluation of the Mechanical Environment in Distraction Osteogenesis. Trans Orthop Res Soc 19(2): 544, 1994.

124. Borodkin JL, Eadie JS, Choi K, Hollister SJ, Goldstein SA: The Effect of Mechanical Stimuli on Bone Ingrowth into Porous Coated Implants. Trans Orthop Res Soc 19(2): 582, 1994.

125. Steen H, Tseng, K-F, Carpenter JE, Goldstein SA: Patella Surface Strain Changes with Removal of Bone Block for ACL Graft. Trans Orthop Res Soc 19(2): 607, 1994.

126. Moore DC, Germiller JA, Grady-Benson JC, Matthews LS, Goldstein SA: Comparison of the Cement Mantle in Proximally-Restricted and Conventionally-Cemented Femoral Strems: Cement Pressure Distributions and Mantle Morphology. Trans Orthop Res Soc 19(2): 814, 1994.

127. Jepsen KJ, Goldstein SA, Kuhn JL, Schaffler MB, Bonadio J: Variations in the Static and Fatigue Properties of Lamellar Bone Associated with Matrix Level Alterations. Trans Orthop Res Soc 20(1):151, 1995.

128. Tseng KF, Goldstein SA, Bonadio J, Schaffler MB: The Effects of Growth Hormone Over-Expression on the Mechanical and Morphological Properties of Murine Cortical Bone. Trans Orthop Res Soc 20(1):152, 1995.

129. Guldberg RE, Goldstein SA, Caldwell NJ, Kuelske CL, Guo XE, Moalli M, Hollister SJ: Mechanical Influences on Trabecular Bone Repair. Trans Orthop Res Soc 20(1):175, 1995.

130. Rouleau JP, Goldstein SA, Fang J, Bonadio J: Direct Gene Transfer Into Fracture Repair Cells in Vivo. Trans Orthop Res Soc 20(1):233, 1995.

131. Guo XE, Liang LC, Goldstein SA: Crack Propagation in Osteonal Cortical Bone: A Linear Fracture Mechanics Analysis. Trans Orthop Res Soc 20(2):301, 1995.

132. Huiskes R, Van Donkelaar CC, Jepsen KJ, Weinans H, Goldstein SA: The Mechanical Consequences of Mineralization in Fetal Bone. Trans Orthop Res Soc 20(2):450, 1995.

133. Germiller JA, Pacifico RJ, Goldstein SA: Effect of Variation in Skeletal Muscle Activity Levels on Bone and Joint Development in the Chick Embryo. Trans Orthop Res Soc 20(2):472, 1995.

134. Eadie JS, Riemer BA, Goldstein SA: Quantification of Vertebral Trabecular Bone Tissue Microstructure. Trans Orthop Res Soc 20(2):528, 1995.

135. Riemer BA, Eadie JS, Wenzel TE, Weisman DE, Guo XE, Goldstein SA: Microstructure and Material Property Variations in Compact and Trabecular Vertebral Bone Tissue. Trans Orthop Res Soc 20(2):529, 1995.

136. Guldberg RE, Richards M, Kuelske CL, Caldwell NJ, Goldstein SA: Trabecular Bone Adaptation Adjacent to Porous-Coated Implants in a Controlled Mechanical Environment. Trans Orthop Res Soc 20(2):555, 1995.

137. Hollister SJ, Guldberg RE, Kuelske CL, Caldwell NJ, Richards M, Goldstein SA: Effects of Healing and Mechanical Stimulus on Bone Adaptation to Porous Coated Implants at Five Weeks. Trans Orthop Res Soc 20(2):556, 1995.

138. Tseng KF, Farley AF, Moore DC, Goldstein SA: Biomechanical Evaluation of Spine Instrumentation Constructs. Trans Orthop Res Soc 20(1):152, 1995.

139. Desbois C, Hagihara K, Pinero G, Boyce, Bonadio J, Tseng KF, Goulet R, Goldstein SA, Loyer E, Bradley, Karsenty G: Increased Bone Formation in Osteocalcin Deficient Mice. Trans JBMS 10(1):S139, 1995.

140. Shapiro F, Tseng KF, Smith E, Goldstein S: Morphologic Comparison Between Normal and Osteogenesis Imperfecta Tibial Cortical Bone with Consequential Biomechanical Properties. Trans JBMS 10(1):S5502, 1995.

141. Zysset PK, Guo X-E, Goldstein SA: A 3D Microstructural Model for Trabecular Bone. American Society of Mechanical Engineers, 1995.

142. Guo X-E, Zysset PK, Goldstein SA: Study of Post-Yield Behavior of Trabecular Bone Using a 3-D Microstructural Model. American Society of Mechanical Engineers, 1995.

143. Guldberg RE, Goldstein SA, Hollister SJ, Caldwell NJ: Mechanical Loading Effects on Extracellular Matrix Organization and Mineral Content During Trabecular Bone Formation. Trans Orthop Res Soc 21(1): 130, 1996.

144. Caldwell NJ, Guldberg RE, Kuelske CL, Kazerooni AC, Goldstein SA: Local Geometry Effects on Bone Ingrowth into Porous-Coated Implants in a Controlled Mechanical Environment. Trans Orthop Res Soc 21(1): 154, 1996.

145. Frankenburg EP, Bauer TW, Jiang M, Poser RD, Goldstein SA: Mechanical Integrity of Calcium Phosphate Cement In In-Vivo Metaphyseal Models Over Time. Trans Orthop Res Soc 21(1): 224, 1996.

146. Cody DD, Gross GJ, Spencer HJ, Goldstein SA: Denistometric and Geometric Predictors of Proximal Femur Mechanics in Response to a Simulated Fall. Trans Orthop Res Soc 21(1): 250, 1996.

147. Richards M, Lewandowski RJ, Senunas LE, Schaffler MB, Goldstein SA, Goulet JA: Regional Differences in New Bone Formation During Distraction To Do Not Extend to Local Macroscopic Architecture. Trans Orthop Res Soc 21(2): 350, 1996.

148. Germiller JA, Shannon G, Bonadio J, Goldstein SA: Chondrocyte Proliferation and Gene Expression in an Embryo Paralysis Model of Altered Long Bone Development. Trans Orthop Res Soc 21(2): 572, 1996.

149. Smith EA, Guo X-E, Goulet RW, Hollister SJ, Goldstein SA: Prediction of Local Strains in Human Vertebral Bone Specimens Using CT-Based Finite Element Models. Trans Orthop Res Soc 21(2): 604, 1996.

150. Rouleau JP, Cook JL, Goldstein SA: The Influence of Cyclic Strain Amplitude and Timing of Mechanical Stimulation on Secondary Fracture Healing. Trans Orthop Res Soc 21(2): 630, 1996.

151. Guldberg RE, Caldwell NJ, Goulet RW, Guo XE, Hollister SJ, Schaffler MB, Goldstein, SA: Mechanical Stimulation of Bone Repair: An Evaluation of In Vivo Tissue Strains in the Hydraulic Bone Chamber Model. Trans Orthop Res Soc 22(1): 114, 1997.

152. Elder SH, Frankenburg EP, Yetkinler DN, Poser RD, Goulet JA, Goldstein SA: Biomechanical Evaluation of Calcium Phosphate Cement-Augmented Repair of Unstable Intertrochanteric Fractures. Trans Orthop Res Soc 22(1): 231, 1997.

153. Richards M, Huibregtse B, Caplan AI, Alsberg E, McDonald AR, Goldstein SA: Marrow-Derived Stromal Cell Injections Influence Bone Regeneration During Distraction. Trans Orthop Res Soc 22(2): 601, 1997.

154. Richards M, Alsberg E, Wineman AS, Goldstein SA, Goulet JA: Increased Distraction Magnitudes Cause Stress Accumulation in Mesenchymal Gap Tissue. Trans Orthop Res Soc 22(2): 708, 1997.

155. Zysset PK. Guo XE, Hoffler CE, Goldstein SA: Elastic Modulus of Human Cortical and Trabecular Tissue Lamellae. Trans Orthop Res Soc 22(2): 798, 1997.

156. Guo XE, Goldstein SA: Vertebral Trabecular Lamellar Modulus Does Not Change in Ovariectomized Rats. Trans Orthop Res Soc 22(2): 921, 1997.

157. Richards M, Weiss JA, Alsberg E, Shibuya T, Schaffler MB, Goldstein SA, Goulet JA: Mechanical Strain Environment Controls New Bone Formation During Distraction Osteogenesis. Trans BED(33); 377-378, ASME 1996.

158. Wenzel TE, Schaffler MB, Goldstein SA: Variations in Collagen Fibril Diameter Distribution in Aging Vertebral Bone. Trans BED(35); 187-188, ASME 1997

159. Richards M, Waanders NA, Weiss JA, Bhatia V, Schaffler MB, Goldstein SA, Goulet JA: Decreased Gap Strains During Distraction Influence the Architecture of Regenerate Bone. BED(35); 501-502, ASME 1997.

160. Richards M, Krauss DJ, McDonald AR, Gibson GJ, Schaffler MB, Goulet JA, Goldstein SA: Increased Distraction Rates Favor Chondrogenesis in the Rat. Trans BED(35); 527-528, ASME 1997.

161. Hoffler CE, Guo XE, Zysset PK, Moore KE, Goldstein SA: Evaluation of Bone Microstructural Properties: Effect of Testing conditions, Depth, Repetition, Time Delay and Displacement Rate. Trans BED (35); 567-568, ASME 1997.

162. Ominsky MS, Zysset PK, Goldstein SA: Elastic Properties of 3D Cells for Trabecular Bone: Digital vs. Structural Finite Element Models, ASME Trans BED (38): 7-8, Nov 1997.

163. Elder SH, Kimura JH, Soslowsky LJ, Goldstein SA: Effects of Compressive Loading on Chondrocyte Differentiation in Agarose Gel Cultures of Chick Limb Bud Cells. Trans ORS, 23(2):912, New Orleans, LA, March 16-19, 1998.

164. Ladd AJC, Goldstein SA, Kinney JH: Finite-Element Modeling of Trabecular Bone: A Direct Comparison With Experiment. Trans ORS, 23(1):112, New Orleans, LA, March 16-19, 1998.

165. Moore KE, Hoffler CE, Zyssett PK, Goldstein SA: Effect of Anatomical Location on Elastic Modulus of Human Bone Tissue Lamellae. Trans ORS, 23(2):560, New Orleans, LA, March 16-19, 1998.

166. Ominsky MS, Hernandez MJ, Yian EH, Demetropoulos D, Banglmaier RF, Goldstein SA, Graziano GP: Enhanced Lumbo-Sacral Fixation Using Buttress Support: Biomechanical Comparison of Intra-Iliac & Intra-Sacral Techniques. Trans, ORS. 23(2): 639, New Orleans, LA, March 16-19, 1998.

167. Richards M, Henne TD, Gibson GJ, Schaffler MB, Goulet JA, Goldstein SA: Increased Distraction Rates Influence the Pathway of Bone Repair But Not Final Architecture. Trans ORS, 23(2):1009, New Orleans, LA, March 16-19, 1998.

168. Richards M, Bhatia V, Weiss JA, Gibson GJ, Schaffler MB, Goulet JA, Goldstein SA: Increased Shear Strains Affect the In Vivo Production of Cartilaginous Collagens During Distraction. Trans ORS, 23(2):598, New Orleans, LA, March 16-19, 1998.

169. Rouleau JP, Cook JL, Goldstein SA: Timing and Magnitude of Interfragmentary Strains Influence Fracture Healing Response. Trans ORS 23(2):553, 1998.

170. Smith EA, Michelson D, Gold PW, Wong M, Mouro CM, Goldstein SA: Mechanical Consequences of Chronic Antidepressant and Anticonvulsant Drug Therapies on Bone. Trans ORS, 23(1):87, New Orleans, LA, March 16-19, 1998.

171. Wenzel TE, Fyhrie DP, Schaffler MB, Goldstein SA: Variations in Three-Dimensional Cancellous Architecture of the Proximal Femur in Hip Fracture Patients and Controls. Trans ORS, 23(1):86, New Orleans, LA, March 16-19, 1998.

172. Elder SH, Frankenburg EP, Yetkinler DN, Poser RD, Goulet JA, Goldstein SA: Biomechanical Evaluation of Calcium Phosphate Cement-Augmented Repair of Unstable Intertrochanteric Fractures. AAOS 65th Annual Meeting, New Orleans, LA, March 19-23, 1998.

173. Loder RT, Hernandez MJ, Lerner AL, Winebrener DJ, Goldstein SA, Hensinger RN, Liu C-Y, Schork MA: The Induction of Congenital Spinal Deformities in Mice by Maternal Carbon Monoxide Exposure. Pediatric Orthopaedic Society of North America, Cleveland, OH, May 7-9, 1998 and Scoliosis Research Society, New York, NY, September 16-20, 1998.

174. Frankenburg EP, Hoffler CE, Shibuya T, Saito M, Baker JA, Goldstein SA: Evaluation of Hydroxyapatite/BIS-GMA Bone Cement for Fixation of Cemented Hip Implants. The Third Combined Meeting of the Orthopaedic Research Societies of the USA, Canada, Europe and Japan, Hamamatsu City, Japan, September 28-30, 1998.

175. Taboas J, Goldstein SA, Buchman S, Kayner D, Mockaitis R, Brennan W, Wang W, Ignelzi M: Controlled Application of Mechanical Forces Leads to Calvaria Suture Fusion. ORS 45th Annual Meeting, Anaheim, CA, February 1-4, 1999.

176. Frankenburg EP, Hoffler CE, Shibuya T, Saito M, Lavagnino M, Baker J, Goldstein SA: Long Term Evaluation of a Hydroxyapatite Composite Cement in Total Hip Arthroplasties. Trans ORS, 24:185, Anaheim, CA, February 1-4, 1999.

177. Hoffler CE, Kozloff K, Moore K, Dillon M, Goldstein SA: Femoral Neck Bone Lamellae Elastic Properties are Independent of Age and Gender. ORS 45th Annual Meeting, Anaheim, CA, February 1-4, 1999.

178. Frankenburg E, Patil P, DeBano C, Bauer T, Poser R, Goldstein SA: A Four and One Half Year Follow-Up of a Bioresorbable Bone Cement in a Canine Metaphyseal Model. ORS 45th Annual Meeting, Anaheim, CA, February 1-4, 1999.

179. Moalli M, Patil P, Machwate M, Harada S, Rodan G, Goldstein SA: Mechanical Load Induces ZIF-268 and C-FOS But Not MSX-2 Early Gene Expression in an In Vivo Model of De Novo Bone Formation. ORS 45th Annual Meeting, Anaheim, CA, February 1-4, 1999.

180. Caldwell N, Orton D, Anderson K, Moalli M, Goldstein SA, Hollister S: Trabecular Bone Adaptation to Controlled Implant Mediated Load. ORS 45th Annual Meeting, Anaheim, CA, February 1-4, 1999.

181. Elder S, Kimura J, Soslowsky L, Goldstein SA: Stimulation of Chondrogenesis by Cyclic Compressive Loading is Frequency-Dependent. ORS 45th Annual Meeting, Anaheim, CA, February 1-4, 1999.

182. Ciarelli T, Schaffler M, Goldstein SA: Age Effects on the Fatigue Behavior of Human Vertebral Cancellous Bone Tissue. ORS 45th Annual Meeting, Anaheim, CA, February 1-4, 1999.

183. Goldstein SA: Skeletal Integrity: The Integration of Biologic and Mechanical Demands. Trans ASME-BED 42:261-262, Big Sky, Montana, June 16-20, 1999.

184. Hoffler CE, Zhang N, Kozloff KM, Grimm MJ, Goldstein SA: Comparison of Scanning Acoustic Microscopy and Nanoindentation Measures of the Elastic Properties of Human Bone Lamellae. Trans ASME-BED 42:315-316, Big Sky, Montana, June 16-20, 1999.

185. Taboas JM, Goldstein SA, Buchman SR, Brennan WA, Mockaitis RP, Wang W, Ignelzi MA: Cyclic Uniaxial Compression Influences Morphogenesis of Loaded and Co-Cultured Cranial Sutures In Vitro. Trans ASME-BED 42:763-764, Big Sky, Montana, June 16-20, 1999.

186. Tseng K-F, Lo W-H, Goldstein SA: The Effects of Exogenous Growth Hormone Administration and Mechanical Over-and Under-Stimulation on the Functional Adaptation of Murine Cortical Bone. Trans ASME-BED 42:411-412, Big Sky, Montana, June 16-20, 1999.

187. Patil PV, Graziano GP, Bonadio J, Goldstein SA: Augmentation of Lumbar Interbody Fusion Using Localized Delivery of an Osteotropic Gene. 6th International Meeting on Advanced Spine Techniques, Vancouver, B.C., Canada, July 8-10, 1999.

188. Moalli MR, Wang S, Caldwell NJ, Maynard CR, Goldstein SA: Intracellular Signaling Responses to Controlled Mechanical Stimulation in an In Vivo Model of Trabecular Bone Formation. ORS 46th Annual Meeting, Orlando, Florida, March 12-15, 2000.

189. McCreadie B, Goldstein SA: Quantitative Measurement of Osteocyte Lacuna Size and Shape from Osteoporotic and Normal Individuals from Confocal Microscopy Images. ORS 46th Annual Meeting, Orlando, Florida, March 12-15, 2000.

190. Patil PV, Graziano GP, Bonadio J, Goldstein SA: Interbody Fusion Augmentation Using Localized Gene Delivery. ORS 46th Annual Meeting, Orlando, Florida, March 12-15, 2000.