Research

The Physical Effects on Tissues In Vivo project group investigates the adaptation response of musculoskeletal tissues when subjected to mechanical stimuli. These projects encompass short-term and long-term adaptation time periods, mechanotransduction events, and signal transduction pathways.

View abstracts from the Physical Effects on Tissues In Vivo project group below.

DEVELOPMENT OF A MECHANICALLY ACTIVE PERFUSION CHAMBER FOR INVESTIGATIONS OF MECHANICAL SIGNAL TRANSDUCTION IN TRABECULAR BONE IN VIVO M.R. Moalli, B. Roessler, N. Caldwell, C. Maynard, S.A. Goldstein

INFLUENCE OF LOADING RATE AND MAGNITUDE ON TRABECULAR BONE ADAPTATION TO MECHANICAL STIMULUS N.J. Caldwell, C.R. Maynard, M.R. Moalli, S.A. Goldstein, K.A. Sweet, B. Nolan, D.C. Kayner, M.W. Stock

INFLUENCE OF TRABECULAR TISSUE DEVELOPMENT TIME ON ADAPTATION TO MECHANICAL STIMULUS N.J. Caldwell, C.R. Maynard, M.M. Moalli, S.A. Goldstein

MECHANICAL LOAD INDUCES ZIF-268 AND C-FOS BUT NOT MSX-2 EARLY GENE EXPRESSION IN AN IN VIVO MODEL OF DE NOVO BONE FORMATION M.R. Moalli, P.V. Patil, M. Machwate, S. Harada, G.A. Rodan, S.A. Goldstein

TRABECULAR BONE RESPONSE TO IMPLANT MEDIATED LOAD N.J. Caldwell, D.G. Orton, K.C. Anderson, J.M. Taboas, M.M. Moalli, S.A. Goldstein, S.J. Hollister, K.A. Sweet, B. Nolan, D.C. Kayner, J. Baker, R. Taylor