Research

The Fracture Healing project group consists of research studies that investigate environmental factors that influence bone repair and regeneration including mechanical forces, tissue engineered constructs, and other methods of biological therapies for applications in clinical orthopaedic science.

View abstracts from the Fracture Healing project group below.

ANABOLIC HORMONES IN BONE: BASIC RESEARCH AND THERAPEUTIC POTENTIAL E.P. Frankenburg, H. Chen, K.A. Sweet, B.T. Nolan, K. Lucas, R.L. Taylor, M.W. Stock, L.K. McCauley, S.A. Goldstein

AUGMENTATION OF BONE REPAIR Patil, P., Bonadio, J., Smiley, E., Debano, C., Nolan, B., Sweet, K., Stock, M., Goldstein, S.

AUGMENTATION OF INTERBODY LUMBAR FUSIONS P.V. Patil, J. Bonadio, R.T. Taylor, K.A. Sweet, B. Nolan, S.A. Goldstein

AUGMENTATION OF LUMBAR INTERBODY FUSION USING LOCALIZED GENE THERAPY D. Scott, E.P. Frankenburg, K.A. Sweet, B. Nolan, R. Taylor, D.C. Kayner, M.W. Stock, J. Wong, S.A. Goldstein

BICONDYLAR TIBIAL PLATEAU FRACTURES: AN EVALUATION OF OPTIMAL FIXATION CONSTRUCTS E. P. Frankenburg, M. A. Karunakar, K. L. Mueller, D. S. Scott, S. Matuszak, P. Pazmino, B.T. Nolan, D. C. Kayner, J. Hall, E. T. Keller, S. A. Goldstein

BIOACTIVE IMPLANT COATING Patil, P.V., Freiberg, A., Levy, R., Goldstein, S.A.

BIOMECHANICAL EVALULATION OF IM NAILING VERSUS PLATING OF DISTAL METAPHYSEAL TIBIA FRACTURES T.T. Le, E.P. Frankenburg, D.S. Scott, K. Oikarinen, B.T. Nolan, D.C. Kayner, J. Hall, E.T. Keller, M.A. Karunakar, J.A. Goulet, S.A. Goldstein

CHARACTERIZATION OF THE MECHANICAL ENVIRONMENT IN MANDIBULAR DISTRACTION OSTEOGENESIS D.G. Orton, M.J. Ignelzi, S. Buchman, S. Rhee, M. Longaker, S.A. Goldstein

EFFECT OF ENDOGENOUS OPIOIDS ON FRACTURE HEALING T. Cooney, E.P. Frankenburg, E. Green, S.A. Goldstein

THE EFFECT OF TOURNIQUET CONTROL ON INTRAMEDULLARY REAMING E.P. Frankenburg, M. Karunakar, D.S. Scott, K.A. Mueller, S. Matuszak, P. Pazmino, R. Taylor, K.A. Sweet, B.T. Nolan, D. Kayner, C. Roehm, S.A. Goldstein

ENHANCED LUMBO-SACRAL FIXATION USING BUTTRESS SUPPORT: BIOMECHANICAL COMPARISON OF INTRA-ILIAC AND INTRA-SACRAL TECHNIQUES M.S. Ominsky, M.J. Hernandez, E. Yian, D. Demetropoulos, R. Banglmaier, M. Stock, D. Kayner, J. Pinto, G. Graziano, S. A. Goldstein

EVALUATION OF HYDROXYAPATITE/BIS-GMA BONE CEMENT FOR FIXATION OF CEMENTED HIP STEMS E.P. Frankenburg, C.E. Hoffler, T. Shibuya, M. Saito, M. Lavagnino, B. Nolan, J.A. Baker, K.A. Sweet, D.C. Kayner, S.A. Goldstein

EVALUATION OF REPAIR BLASTEMA CELLS IN THE HEALING PROCESS OF BONE K.M. Kozloff, E.P. Frankenburg, E.A. Smith, B.T. Nolan, K. Lucas, R.L. Taylor, J.A. Baker, K.A. Sweet, S.A. Goldstein

FOCAL ADHESION KINASE EXPRESSION DURING MANDIBULAR DISTRACTION OSTEOGENESIS S. Buchman, M. Ignelzi, L. Tong, S. Rhee, D. Kayner, M. Stock

FOUR AND ONE HALF YEAR FOLLOW-UP OF A BIORESORBABLE BONE CEMENT IN A CANINE METAPHYSEAL MODEL E.P. Frankenburg, P.V. Patil, C.M. DeBano, K.A. Sweet, J.A. Baker, M.R. Moalli, B.T. Nolan, D.C. Kayner, M.W. Stock, R.L. Taylor, S.A. Goldstein, T.W. Baue*, R.D. Poser

INCREASED DISTRACTION RATES INFLUENCE PRECURSOR TISSUE COMPOSITION WITHOUT AFFECTING BONE REGENERATION M. Richards, K.M. Kozloff, J.A. Goulet, S.A. Goldstein

INFLUENCE OF MARROW ABLATION ON OSTEOGENESIS AFTER DISTRACTION E.P. Frankenburg, K.M. Kozloff, E.A. Smith, T. Adachi, J.A. Baker, K.A. Sweet, B. Nolan, A.I. Caplan, S.A. Goldstein

INFLUENCE OF MECHANICAL STRAIN ENVIRONMENT ON PATTERNS OF GENE EXPRESSION DURING SECONDARY FRACTURE HEALING E.A. Smith, S.K. Volkman, S.A. Goldstein, M.R. Moalli, J.A. Goulet, B.T. Nolan, K.A. Sweet, D.C. Kayner, M.W. Stock

LOCALIZED GENE THERAPY TO STIMULATE BONE REPAIR D. Scott, E.P. Frankenburg, K.A. Sweet, B. Nolan, R. Taylor, D.C. Kayner, M.W. Stock, S. A. Goldstein

MARROW-DERIVED STROMAL CELL INJECTIONS INFLUENCE OSTEOGENESIS AFTER DISTRACTION E.P. Frankenburg, K.M. Kozloff, E.A. Smith, K.A. Sweet, B.T. Nolan, A.I. Caplan, S.A. Goldstein

MOBILITY OF INDIUM-LABELED MESENCHYMAL PROGENITOR CELLS DURING AUGMENTATION OF BONE REPAIR FOLLOWING DISTRACTION OSTEOGENESIS K.M. Kozloff, E.P. Frankenburg, L.A. Solchaga, E.A. Smith-Adaline, J.C. Taylor, D.P. Lennon, J.E. Dennis, J. Gao, M.R. Kilbourn, A.I. Caplan, S.A. Goldstein

TISSUE ENGINEERING OF TENDONS AND LIGAMENTS P.V. Patil, K.M. Kozloff, J.E. Carpenter, S.A. Goldstein